The Gunners already have a Double Gameweek 23 so they now have five matches over the next three Gameweeks, more than any other side.
Gabriel (£5.2m) offers the greatest goal threat of their defenders, while Bukayo Saka (£8.3m), Martin Odegaard (£7.0m) and Eddie Nketiah (£6.7m) all have the potential for major hauls in attack.
Everton centre-back James Tarkowski (£4.2m) is an enticing option. He scored and earned 15 points in their first match under Sean Dyche against Arsenal last weekend.
Wolves defenders Max Kilman (£4.3m) and Craig Dawson (£4.8m) also both earned double-figure hauls in their 3-0 win over Liverpool.
Midfielder Ruben Neves (£5.4m) is their top-scoring outfield player this season on 77 points, netting his fifth goal of the campaign last weekend.
Investing in Liverpool will be the key decision for managers.
The Reds are in poor form at both ends of the pitch, scoring once in their last four matches and conceding three goals in three of those outings.
Mohamed Salah (£12.7m) would typically be the go-to captain for a Double Gameweek, but the Egyptian has now gone five matches without a goal or an assist.
Nonetheless, Salah's potential for major hauls may well tempt many owners of Bruno Fernandes (£9.9m) to make a short-term move to cover Man Utd’s blank.